BDBM443368 1′-Cyano-N-(4-fluorophenyl)-2-oxo-1,2-dihydrospiro[pyrido[2,3-b][1,4]oxazine-3,3′-pyrrolidine]-6-carboxamide::US10654853, Example 141::US11236092, Example 141

SMILES Fc1ccc(NC(=O)c2ccc3NC(=O)C4(CCN(C4)C#N)Oc3n2)cc1

InChI Key InChIKey=CJALBJJHSYATKP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 443368   

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 443368BDBM443368(US10654853, Example 141 | 1′-Cyano-N-(4-fluo...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 443368BDBM443368(US10654853, Example 141 | 1′-Cyano-N-(4-fluo...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2021
Entry Details
US Patent