BDBM443374 2-Oxo-6-phenyl-1,4-dihydro-2H-spiro[pyrido[2,3-b]pyrazine-3,3′-pyrrolidine]-1′-carbonitrile::US10654853, Example 147::US11236092, Example 147

SMILES O=C1Nc2ccc(nc2NC11CCN(C1)C#N)-c1ccccc1

InChI Key InChIKey=TYZJHOTUKGSKAO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 443374   

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 443374BDBM443374(US10654853, Example 147 | 2-Oxo-6-phenyl-1,4-dihyd...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2021
Entry Details
US Patent

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 443374BDBM443374(US10654853, Example 147 | 2-Oxo-6-phenyl-1,4-dihyd...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent