BDBM445124 (2S,4S)-1-cyano-N-methyl-4- phenyl-N-(4-phenylthiazol-2- yl)pyrrolidine-2-carboxamide::US10669234, Example 63::US11319287, Example 63

SMILES CN(C(=O)[C@@H]1C[C@H](CN1C#N)c1ccccc1)c1nc(cs1)-c1ccccc1

InChI Key InChIKey=RQELPKFGBFTZSL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445124   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 445124BDBM445124(US10669234, Example 63 | (2S,4S)-1-cyano-N-methyl-...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 445124BDBM445124(US10669234, Example 63 | (2S,4S)-1-cyano-N-methyl-...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent