BDBM445126 (S)-1-cyano-N-(3-(3- methoxyphenyl)isoxazol- 5-yl)-N-methylpyrrolidine- 2-carboxamide::US10669234, Example 65::US11319287, Example 65

SMILES COc1cccc(c1)-c1cc(on1)N(C)C(=O)[C@@H]1CCCN1C#N

InChI Key InChIKey=KCPHOFOOLGXKGK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 445126   

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 445126BDBM445126(US10669234, Example 65 | (S)-1-cyano-N-(3-(3- meth...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 445126BDBM445126(US10669234, Example 65 | (S)-1-cyano-N-(3-(3- meth...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 445126BDBM445126(US10669234, Example 65 | (S)-1-cyano-N-(3-(3- meth...)
Affinity DataIC50: 5.50E+4nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 445126BDBM445126(US10669234, Example 65 | (S)-1-cyano-N-(3-(3- meth...)
Affinity DataIC50: 5.50E+4nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent