BDBM445146 (S)-2-(6-(1H-Imidazol-2-yl)-4-phenylindoline-1-carbonyl)pyrrolidine-1-carbonitrile::US10669234, Example 90::US11319287, Example 90

SMILES CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)N1CCc2c(-c3ccccc3)cc(-c3ncc[nH]3)cc21

InChI Key InChIKey=ZBKMMWZJRWVUKF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 445146   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 445146BDBM445146(US10669234, Example 90 | (S)-2-(6-(1H-Imidazol-2-y...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 445146BDBM445146(US10669234, Example 90 | (S)-2-(6-(1H-Imidazol-2-y...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 445146BDBM445146(US10669234, Example 90 | (S)-2-(6-(1H-Imidazol-2-y...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 445146BDBM445146(US10669234, Example 90 | (S)-2-(6-(1H-Imidazol-2-y...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent