BDBM445679 (R)-(3-(2,5-dimethylthiazol- 4-yl)-8-methyl-5,6-dihydro- [1,2,4]triazolo[4,3-a]pyrazin- 7(8H)-yl)(4-(thiophen-2- yl)phenyl)methanone::US10683295, Compound 16

SMILES C[C@@H]1C2NNC(N2CCN1C(=O)c1ccc(cc1)-c1cccs1)c1nc(C)sc1C

InChI Key InChIKey=CSJHHOJGIBJJNV-ZJDGCUJOSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 445679   

TargetNeuromedin-K receptor(Homo sapiens (Human))
Ogeda

US Patent
LigandPNGBDBM445679((R)-(3-(2,5-dimethylthiazol- 4-yl)-8-methyl-5,6-di...)
Affinity DataKi:  32nMAssay Description:NK3: The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an in vit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent