BDBM445997 US10669246, Example 48::US10968188, Example 48
SMILES Cc1c(F)cncc1-c1ccc2nc(NC(=O)C3CC3(F)F)sc2c1
InChI Key InChIKey=KDBAVXCYWFLJIK-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 445997
Affinity DataIC50: 7.90nMAssay Description:c-abl kinase activity was measured by Promega's ADP-Glo™ Assay. In this assay, His-tagged recombinant human ABL1 (0.25 ng/μl) is incubated w...More data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:ADP-Glo assay kit was purchased from Promega. Magnesium chloride (MgCl2), bovine serum albumin (BSA), ethylene glycol-bis(β-aminoethyl ether)-N,...More data for this Ligand-Target Pair