BDBM448014 US10689367, Example 342.0::US10689367, Example 343.0

SMILES CC[C@H](c1cc(F)cc(F)c1)n1c(NS(=O)(=O)[C@@H](C)[C@H](OC)c2ncc(Cl)cn2)nnc1-c1cccc(OC)n1

InChI Key InChIKey=FJYDFUZXLFKLQK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448014   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM448014(US10689367, Example 343.0 | US10689367, Example 34...)
Affinity DataEC50:  0.0500nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM448014(US10689367, Example 343.0 | US10689367, Example 34...)
Affinity DataEC50:  0.100nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent