BDBM448403 1-{[6-(3,3-Dimethylazetidin-1-yl)-2-methylpyridin-3-yl]methyl}-N-[(6R)-3-methyl-2H,4H,5H,6H-::US10695334, Example 67

SMILES Cc1[nH]nc2[C@@H](CCc12)NC(=O)c1cnn(Cc2ccc(nc2C)N2CC(C)(C)C2)c1

InChI Key

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 448403   

TargetPlasma kallikrein(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448403(1-{[6-(3,3-Dimethylazetidin-1-yl)-2-methylpyridin-...)
Affinity DataKi:  1nMAssay Description:Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent