BDBM448416 1-[(6-{3-Azabicyclo[3.1.0]hexan-3-yl}-2-cyano-::US10695334, Example 105
SMILES Cc1[nH]nc2C(CCc12)NC(=O)c1cn(Cc2ccc(nc2C#N)N2CC3CC3C2)cn1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 448416
Affinity DataKi: 1nMAssay Description:Human PKK (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295 f...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair