BDBM448530 7-(1,5-dimethylindazol-4-yl)-N-methyl-3,5-dihydro-2H-1,4-benzoxazepine-4-carboxamide::US10696655, Example 3::US11168070, Example 3

SMILES CNC(=O)N1CCOc2ccc(cc2C1)-c1c(C)ccc2n(C)ncc12

InChI Key InChIKey=VREYOTRCCHNZLF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448530   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 448530BDBM448530(US10696655, Example 3 | 7-(1,5-dimethylindazol-4-y...)
Affinity DataIC50: 57nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 448530BDBM448530(US10696655, Example 3 | 7-(1,5-dimethylindazol-4-y...)
Affinity DataIC50: 57nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent