BDBM448655 N-methyl-2-(3-(1-methyl-1H-pyrazol-4-yl)isoquinolin-8-yl)benzo[d]oxazole-4-carboxamide::US10696655, Example 121::US11168070, Example 121

SMILES CNC(=O)c1cccc2oc(nc12)-c1cccc2cc(ncc12)-c1cnn(C)c1

InChI Key InChIKey=BHOQOECVNLRMPT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448655   

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 448655BDBM448655(US10696655, Example 121 | N-methyl-2-(3-(1-methyl-...)
Affinity DataIC50: 274nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 448655BDBM448655(US10696655, Example 121 | N-methyl-2-(3-(1-methyl-...)
Affinity DataIC50: 274nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
US Patent