BDBM450472 Cis-4-(1-acryloyloctahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-3-fluoro-9H-carbazole-1-carboxamide (Single Enantiomers)::US10676434, Example 121

SMILES NC(=O)c1cc(F)c(N2C[C@H]3CCCN([C@H]3C2)C(=O)C=C)c2c3ccccc3[nH]c12

InChI Key InChIKey=SKOGEEJVYOZNCB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 450472   

TargetTyrosine-protein kinase BTK(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM450472(US10676434, Example 121 | Cis-4-(1-acryloyloctahyd...)
Affinity DataIC50: 0.100nMAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2021
Entry Details
US Patent