BDBM451069 US10676479, Example 99::ethyl 5-((2-fluoro-6-methoxybenzyl)amino)-8-(2-

SMILES CCOC(=O)c1ncn2c(NCc3c(F)cccc3OC)ncc(-c3cccnc3C)c12

InChI Key InChIKey=QYRDDWOUVQBZGU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 451069   

LigandChemical structure of BindingDB Monomer ID 451069BDBM451069(US10676479, Example 99 | ethyl 5-((2-fluoro-6-meth...)
Affinity DataIC50: 14.6nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 451069BDBM451069(US10676479, Example 99 | ethyl 5-((2-fluoro-6-meth...)
Affinity DataIC50: 16nMAssay Description:To assess the compounds' potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 451069BDBM451069(US10676479, Example 99 | ethyl 5-((2-fluoro-6-meth...)
Affinity DataIC50: 68.6nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
US Patent