BDBM454188 US10717708, Example 76::US11186544, Example 76::US11530183, Example 76

SMILES Clc1ccc(NC(=O)N[C@@H]2CCCN(C2=O)c2ccc(cc2)-c2ccccc2C#N)cc1

InChI Key InChIKey=HNTPAGSPYUWUCG-HSZRJFAPSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 454188   

TargetN-formyl peptide receptor 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM454188(US10717708, Example 76 | US11186544, Example 76 | ...)
Affinity DataEC50:  0.810nMAssay Description:FPR2 and FPR1 Cyclic Adenosine Monophosphate (cAMP) Assays. A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetfMet-Leu-Phe receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM454188(US10717708, Example 76 | US11186544, Example 76 | ...)
Affinity DataEC50:  10nMAssay Description:FPR2 and FPR1 Cyclic Adenosine Monophosphate (cAMP) Assays. A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetfMet-Leu-Phe receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM454188(US10717708, Example 76 | US11186544, Example 76 | ...)
Affinity DataEC50:  10nMAssay Description:A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetFibroblast growth factor receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM454188(US10717708, Example 76 | US11186544, Example 76 | ...)
Affinity DataEC50:  10nMAssay Description:A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetN-formyl peptide receptor 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM454188(US10717708, Example 76 | US11186544, Example 76 | ...)
Affinity DataEC50:  0.810nMAssay Description:A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetFibroblast growth factor receptor 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM454188(US10717708, Example 76 | US11186544, Example 76 | ...)
Affinity DataEC50:  0.810nMAssay Description:A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent