BDBM4542 4-Phenylamino-3-quinolinecarbonitrile deriv. 2b::4-[(2-Chloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-morpholinyl)propoxy]-3-quinolinecarbonitrile::4-[(2-chloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(morpholin-4-yl)propoxy]quinoline-3-carbonitrile

SMILES COc1ccc(Cl)c(Nc2c(cnc3cc(OCCCN4CCOCC4)c(OC)cc23)C#N)c1

InChI Key InChIKey=GJTWFSFZLIOXFD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4542   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4542(4-[(2-chloro-5-methoxyphenyl)amino]-6-methoxy-7-[3...)
Affinity DataIC50: 1.60nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed