BDBM454949 US10730870, Example 116::US11512083, Example 116

SMILES CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(C2=CCCC2)cc1)N1Cc2ccccc2C1=O

InChI Key InChIKey=ZTDMSABBFAEYOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 454949   

TargetVHL complex(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 454949BDBM454949(US10730870, Example 116 | US11512083, Example 116)
Affinity DataIC50: 3.90E+3nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent

Targetvon Hippel-Lindau disease tumor suppressor(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 454949BDBM454949(US10730870, Example 116 | US11512083, Example 116)
Affinity DataIC50: 3.90E+3nMAssay Description:Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent