BDBM455214 US10730874, Compound I-227b

SMILES OC(=O)CC(NC(=O)c1cn(Cc2cn3cc(ccc3n2)C2CC2)nn1)c1ncn2ccc(Cl)c(F)c12

InChI Key InChIKey=ZKQQNXGQJQBXIJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 455214   

TargetPlasma kallikrein(Homo sapiens (Human))
Shire Human Genetic Therapies

US Patent
LigandPNGBDBM455214(US10730874, Compound I-227b)
Affinity DataEC50:  1.05E+3nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent