BDBM455222 US10730874, Compound I-235::US11352356, Compound I-235

SMILES Fc1c(Cl)ccn2cnc(CNC(=O)c3cn(Cc4cc5ccc(cc5[nH]4)C4CC4)nn3)c12

InChI Key InChIKey=QYHIARHHDXPSGM-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 455222   

TargetPlasma kallikrein(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM455222(US10730874, Compound I-235 | US11352356, Compound ...)
Affinity DataEC50:  1.05E+3nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM455222(US10730874, Compound I-235 | US11352356, Compound ...)
Affinity DataEC50:  1.05E+3nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent