BDBM455226 US10730874, Compound I-239

SMILES Fc1cc2nc(Cn3cc(nn3)C(=O)OCc3ncn4ccc(Cl)c(F)c34)cn2cc1C1CC1

InChI Key InChIKey=SDJSFAPPNYFXTA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 455226   

TargetPlasma kallikrein(Homo sapiens (Human))
Shire Human Genetic Therapies

US Patent
LigandPNGBDBM455226(US10730874, Compound I-239)
Affinity DataEC50:  5.5nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent