BDBM455427 US20260116867, Compound A2

SMILES CC(=O)Nc1cc(Oc2cccc3c2C(=O)N(C2CCC(=O)NC2=O)C3=O)cc(C(C)(C)C)c1

InChI Key InChIKey=NFBBXPBQJJYUTN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 455427   

TargetProtein cereblon(Human)
ST. JUDE CHILDREN''S RESEARCH HOSPITAL

US Patent
LigandChemical structure of BindingDB Monomer ID 455427BDBM455427(US20260116867, Compound A2)
Affinity DataEC50:  11nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
US Patent