BDBM455870 4-(3-(cyclopropylethynyl)-2- (1-(hydroxyamino)-1-oxo-3- phenylpropan-2-yl)-2H- indazol-5-yl)benzamide::US10723705, No. I-0026

SMILES NC(=O)c1ccc(cc1)-c1ccc2nn(C(Cc3ccccc3)C(=O)NO)c(C#CC3CC3)c2c1

InChI Key InChIKey=ZTENLURKCUAVGO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 455870   

TargetHistone deacetylase 8(Human)
Incyte

US Patent
LigandPNGBDBM455870(4-(3-(cyclopropylethynyl)-2- (1-(hydroxyamino)-1-o...)
Affinity DataIC50: 50nMAssay Description:HDAC-Glo I/II Assay Kit was purchased from Promega Corporation (Madison, Wis.), including the following components: HDAC-Glo I/II Buffer (25 mM Tris ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
US Patent