BDBM455914 N-hydroxy-3- phenyl-2-(4- (pyridin-4-yl)-1H- pyrazolo[4,3- c]pyridin-1- yl)propanamide::US10723705, No. I-0070

SMILES ONC(=O)C(Cc1ccccc1)n1ncc2c(nccc12)-c1ccncc1

InChI Key InChIKey=VRXKJSSHQDYGLZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 455914   

TargetHistone deacetylase 8(Human)
Incyte

US Patent
LigandPNGBDBM455914(N-hydroxy-3- phenyl-2-(4- (pyridin-4-yl)-1H- pyraz...)
Affinity DataIC50: 125nMAssay Description:HDAC-Glo I/II Assay Kit was purchased from Promega Corporation (Madison, Wis.), including the following components: HDAC-Glo I/II Buffer (25 mM Tris ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
US Patent