BDBM455918 N-hydroxy-3- phenyl-2-(5- (pyrimidin-5-yl)-1H- pyrazolo[4,3- b]pyridin-1- yl)propanamide::US10723705, No. I-0074

SMILES ONC(=O)C(Cc1ccccc1)n1ncc2nc(ccc12)-c1cncnc1

InChI Key InChIKey=DUAGDFLGGPOLQU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 455918   

TargetHistone deacetylase 8(Human)
Incyte

US Patent
LigandPNGBDBM455918(N-hydroxy-3- phenyl-2-(5- (pyrimidin-5-yl)-1H- pyr...)
Affinity DataIC50: 125nMAssay Description:HDAC-Glo I/II Assay Kit was purchased from Promega Corporation (Madison, Wis.), including the following components: HDAC-Glo I/II Buffer (25 mM Tris ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
US Patent