BDBM455983 4-(3- (cyclopropylethynyl)-2- (1-(hydroxyamino)-1- oxo-3-phenylpropan-2- yl)-2H-pyrazolo[3,4- c]pyridin-7-yl)benzamide::US10723705, No. I-0140

SMILES NC(=O)c1ccc(cc1)-c1nccc2c(C#CC3CC3)n(nc12)C(Cc1ccccc1)C(=O)NO

InChI Key InChIKey=GRFAWGKDNOLICK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 455983   

TargetHistone deacetylase 8(Human)
Incyte

US Patent
LigandPNGBDBM455983(4-(3- (cyclopropylethynyl)-2- (1-(hydroxyamino)-1-...)
Affinity DataIC50: 50nMAssay Description:HDAC-Glo I/II Assay Kit was purchased from Promega Corporation (Madison, Wis.), including the following components: HDAC-Glo I/II Buffer (25 mM Tris ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
US Patent