BDBM458591 US10745401, Example 65::US11466007, Example 65

SMILES Cc1c2c(CCN(CCN3CCN(CC3)c3nsc4ccccc34)C2=O)nn1C

InChI Key InChIKey=UMDLGBGKSYLCIH-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 458591   

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM458591(US10745401, Example 65 | US11466007, Example 65)
Affinity DataKi:  0.150nMAssay Description:Present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following procedures. CHO cell membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM458591(US10745401, Example 65 | US11466007, Example 65)
Affinity DataKi:  0.150nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM458591(US10745401, Example 65 | US11466007, Example 65)
Affinity DataKi:  0.900nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM458591(US10745401, Example 65 | US11466007, Example 65)
Affinity DataKi:  0.900nMAssay Description:Present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following procedures. CHO cell membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(2) dopamine receptor(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM458591(US10745401, Example 65 | US11466007, Example 65)
Affinity DataKi:  222nMAssay Description:Present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following procedures. CHO cell membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(2) dopamine receptor(Human)
Sumitomo Pharma

US Patent
LigandPNGBDBM458591(US10745401, Example 65 | US11466007, Example 65)
Affinity DataKi:  222nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent