BDBM458629 5-{2-[4-(1,2-Benzoisoxazol-3-yl)piperidin-1-yl]ethyl}-1-methyl-5,6,7,8-tetrahydropyrrolo[3,2-c]azepin-4(1H)-one::US10745401, Example 103::US11466007, Example 103

SMILES Cn1ccc2c1CCCN(CCN1CCC(CC1)c1noc3ccccc13)C2=O

InChI Key InChIKey=GDZBFHVIKHSMAN-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 458629   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM458629(5-{2-[4-(1,2-Benzoisoxazol-3-yl)piperidin-1-yl]eth...)
Affinity DataKi:  0.470nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM458629(5-{2-[4-(1,2-Benzoisoxazol-3-yl)piperidin-1-yl]eth...)
Affinity DataKi:  0.470nMAssay Description:Present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following procedures. CHO cell membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Sumitomo Pharma

US Patent
LigandPNGBDBM458629(5-{2-[4-(1,2-Benzoisoxazol-3-yl)piperidin-1-yl]eth...)
Affinity DataKi:  0.800nMAssay Description:Present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following procedures. CHO cell membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Sumitomo Pharma

US Patent
LigandPNGBDBM458629(5-{2-[4-(1,2-Benzoisoxazol-3-yl)piperidin-1-yl]eth...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Sumitomo Pharma

US Patent
LigandPNGBDBM458629(5-{2-[4-(1,2-Benzoisoxazol-3-yl)piperidin-1-yl]eth...)
Affinity DataKi:  129nMAssay Description:Present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following procedures. CHO cell membrane ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Sumitomo Pharma

US Patent
LigandPNGBDBM458629(5-{2-[4-(1,2-Benzoisoxazol-3-yl)piperidin-1-yl]eth...)
Affinity DataKi:  129nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent