BDBM45884 4-(1-imidazolylmethyl)pyridine::4-(imidazol-1-ylmethyl)pyridine::MLS-0091917.0001::US9394290, 2::cid_14424120

SMILES C(c1ccncc1)n1ccnc1

InChI Key InChIKey=SQVMDVNVWYRZFV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 45884   

TargetCytochrome P450 11B1, mitochondrial(Human)
Universitaet Des Saarlandes Campus Saarbruecken

US Patent
LigandPNGBDBM45884(4-(1-imidazolylmethyl)pyridine | MLS-0091917.0001 ...)
Affinity DataIC50: 663nMT: 2°CAssay Description:V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Universitaet Des Saarlandes Campus Saarbruecken

US Patent
LigandPNGBDBM45884(4-(1-imidazolylmethyl)pyridine | MLS-0091917.0001 ...)
Affinity DataIC50: 663nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM45884(4-(1-imidazolylmethyl)pyridine | MLS-0091917.0001 ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM45884(4-(1-imidazolylmethyl)pyridine | MLS-0091917.0001 ...)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM45884(4-(1-imidazolylmethyl)pyridine | MLS-0091917.0001 ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay