BDBM459230 US10759805, Ex 34

SMILES C[C@H](c1ccccc1)n1c(=O)[nH]c2cc3[nH]nc(NC(C)=O)c3cc2c1=O

InChI Key InChIKey=MQRPRAWAQFFLKP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 459230   

TargetMitogen-activated protein kinase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM459230(US10759805, Ex 34)
Affinity DataIC50: 2.30E+3nMAssay Description:Human: Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
US Patent