BDBM459443 US10752635, Example 4, Peak 1::US11492354, Example 4, Peak 1
SMILES COc1cccc(F)c1-c1nccc(n1)C(=O)Nc1cc(F)c2n(C)ncc2c1N1CC[C@@H](N)C1
InChI Key InChIKey=PSZVRCRTXCCMNS-CYBMUJFWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 459443
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileumMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Incyte Research Institute
Curated by ChEMBL
Incyte Research Institute
Curated by ChEMBL
Affinity DataKi: 105nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
Affinity DataIC50: 846nMAssay Description:The compound was tested for beta-adrenergic activity against Beta-2 adrenergic receptor from guinea pig trachea.More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against human carbonic anhydrase II using pH stat assayMore data for this Ligand-Target Pair