BDBM462467 US10766903, Example 80

SMILES Cn1nc2c(ncn(CC3(O)CCN(CC3)C(=O)C[C@@H](C(F)F)c3ccccc3)c2=O)c1-c1ccc(CN)cc1

InChI Key InChIKey=YBDNJHPVTVYIFV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 462467   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Almac Discovery

US Patent
LigandPNGBDBM462467(US10766903, Example 80)
Affinity DataIC50: 250nMAssay Description:USP7 activity was monitored in a fluorescence polarisation (FP) homogeneous assay using the isopeptide ubiquitin-Lys-TAMRA substrate (U-558, Boston B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent