BDBM462568 3-((4-hydroxy-1- ((R)-3- phenylbutanoyl) piperidin-4- yl)methyl)-6- ((1R,5S)-3-methyl- 3,6- diazabicyclo[3.2.1] octan-6- yl)pyrimidin-4(3H)- one [first eluted by analytical SFC:::US10766903, Example 180

SMILES C[C@H](CC(=O)N1CCC(O)(Cn2cnc(cc2=O)N2C[C@@H]3C[C@H]2CN(C)C3)CC1)c1ccccc1

InChI Key InChIKey=ARCMLXVLWVMKQC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 462568   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Almac Discovery

US Patent
LigandPNGBDBM462568(3-((4-hydroxy-1- ((R)-3- phenylbutanoyl) piperidin...)
Affinity DataIC50: 250nMAssay Description:USP7 activity was monitored in a fluorescence polarisation (FP) homogeneous assay using the isopeptide ubiquitin-Lys-TAMRA substrate (U-558, Boston B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent