BDBM465358 N-(3′-(8-chloro-6-((2-hydroxyethylamino)methyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-2,2′-dimethylbiphenyl-3-yl)-5-((2-hydroxyethylamino)methyl)picolinamide::US10793565, Example 1::US11566026, Example 1

SMILES Cc1c(NC(=O)c2ccc(CNCCO)cn2)cccc1-c1cccc(-c2nc3c(Cl)cc(CNCCO)cn3n2)c1C

InChI Key InChIKey=YSAJDSJDUYIVMO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 465358   

LigandPNGBDBM465358(US10793565, Example 1 | N-(3′-(8-chloro-6-((...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM465358(US10793565, Example 1 | N-(3′-(8-chloro-6-((...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2023
Entry Details
US Patent