BDBM465361 2-((8-chloro-2-(2,2′-dimethyl-3′-(4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)biphenyl-3-yl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl)methylamino)ethanol::US10793565, Example 4::US11566026, Example 4

SMILES Cc1c(cccc1-c1cccc(-c2nc3CCNCc3s2)c1C)-c1nc2c(Cl)cc(CNCCO)cn2n1

InChI Key InChIKey=UVJSDBOSRJZZGH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 465361   

LigandPNGBDBM465361(US10793565, Example 4 | 2-((8-chloro-2-(2,2′...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM465361(US10793565, Example 4 | 2-((8-chloro-2-(2,2′...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2023
Entry Details
US Patent