BDBM466875 US10800767, Example 19

SMILES CC(C)c1cc(nn(C)c1=O)S(=O)(=O)c1c(Cl)cc(NCc2noc(=O)[nH]2)cc1Cl

InChI Key InChIKey=URKZEWOGYPDEQW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 466875   

TargetThyroid hormone receptor alpha(Human)
Terns

US Patent
LigandPNGBDBM466875(US10800767, Example 19)
Affinity DataEC50:  1.93E+3nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor beta(Human)
Terns

US Patent
LigandPNGBDBM466875(US10800767, Example 19)
Affinity DataEC50: >5.00E+3nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent