BDBM466947 3-((2,2-difluorocyclopropyl)methyl)- 7-(4-fluoro-3-methylphenyl)-[1,2,4] triazole[4,3-a]pyridine::US10800776, Example 27

SMILES Cc1cc(ccc1F)-c1ccn2c(CC3CC3(F)F)nnc2c1

InChI Key InChIKey=FHWGKKFJEBBHDR-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 466947   

TargetMetabotropic glutamate receptor 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466947(3-((2,2-difluorocyclopropyl)methyl)- 7-(4-fluoro-3...)
Affinity DataEC50:  868nMAssay Description:Experimental materials: HEK/mGluR2 cell line (human GluR2 transfected HEK cell line), DMEM (FBS) medium, positive control LY487379 (purchased from si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM466947(3-((2,2-difluorocyclopropyl)methyl)- 7-(4-fluoro-3...)
Affinity DataIC50: 4.00E+4nMAssay Description:Experimental method: hERG patch clamp detection methodExperimental procedure: Compound preparation: the stock solution of a compound was diluted with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent