BDBM468660 US10807952, Cmp No. 64::US11001600, Cmp No. 49::tert-butyl ((3'- ((2S,4R)-1-(2-(3- carbamoyl-1H- indazol-1- yl)acetyl)-4- fluoropyrrolidine-2- carboxamido)-2'- fluoro-[1,1'- biphenyl]-3- yl)(methyl)(oxo)- $#9633;6-sulfanylidene)- $#9633;4- azanecarboxylate

SMILES CC(C)(C)OC(=O)N=S(C)(=O)c1cccc(c1)-c1cccc(NC(=O)[C@@H]2C[C@@H](F)CN2C(=O)Cn2nc(C(N)=O)c3ccccc23)c1F

InChI Key InChIKey=XHVDNUMPHJUJNQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 468660   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM468660(tert-butyl ((3'- ((2S,4R)-1-(2-(3- carbamoyl-1H- i...)
Affinity DataIC50: 5.50E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM468660(tert-butyl ((3'- ((2S,4R)-1-(2-(3- carbamoyl-1H- i...)
Affinity DataIC50: 5.50E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent