BDBM46897 5-tert-Butyl-3-methyl-furan-2-carboxylic acid cyclopentylcarbamoylmethyl-(2,6-dimethyl-phenyl)-amide::5-tert-butyl-N-[2-(cyclopentylamino)-2-keto-ethyl]-N-(2,6-dimethylphenyl)-3-methyl-2-furamide::5-tert-butyl-N-[2-(cyclopentylamino)-2-oxidanylidene-ethyl]-N-(2,6-dimethylphenyl)-3-methyl-furan-2-carboxamide::5-tert-butyl-N-[2-(cyclopentylamino)-2-oxoethyl]-N-(2,6-dimethylphenyl)-3-methyl-2-furancarboxamide::5-tert-butyl-N-[2-(cyclopentylamino)-2-oxoethyl]-N-(2,6-dimethylphenyl)-3-methylfuran-2-carboxamide::MLS000556811::SMR000173544::cid_1454983

SMILES COc1noc2cc(N3CCOc4cc(C(=O)N5CCCCC5)cnc43)ccc12

InChI Key InChIKey=ADFOFBMTHOLHHF-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 46897   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Kyorin Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 46897BDBM46897(US12577217, Example 1-20)
Affinity DataIC50: 10nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2026
Entry Details
US Patent