BDBM470885 US10821115, Example 270::US11224601, Example 270

SMILES CO[C@@]1(CN2CCN(CC(O)=O)CC2)\C=C\C[C@H](C)[C@@H](C)S(=O)(=O)NC(=O)c2ccc3OC[C@]4(CCCc5cc(Cl)ccc45)CN(C[C@@H]4CC[C@@H]14)c3c2

InChI Key InChIKey=GWLFWYRUOYTGTC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 470885   

LigandPNGBDBM470885(US10821115, Example 270 | US11224601, Example 270)
Affinity DataIC50: 0.0350nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2021
Entry Details
US Patent

LigandPNGBDBM470885(US10821115, Example 270 | US11224601, Example 270)
Affinity DataIC50: 0.0350nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent