BDBM471432 US10821115, Example 100447::US11224601, Example 100447

SMILES [#6]-[#8][C@@]1([#6]\[#6]=[#6](\[#6])-[#6])\[#6]=[#6]\[#6]-[#6@H](-[#6])-[#6@@H](-[#6])S(=O)(=O)[#7]-[#6](=O)-c2ccc3-[#8]-[#6][C@]4([#6]-[#6]-[#6]-c5cc(Cl)ccc45)[#6]-[#7](-[#6]-[#6@@H]-4-[#6]-[#6]-[#6@@H]1-4)-c3c2

InChI Key InChIKey=QLINQFLXEQLRDX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 471432   

LigandPNGBDBM471432(US10821115, Example 100447 | US11224601, Example 1...)
Affinity DataIC50: 0.0500nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
US Patent

LigandPNGBDBM471432(US10821115, Example 100447 | US11224601, Example 1...)
Affinity DataIC50: 0.0500nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2021
Entry Details
US Patent