BDBM471611 US10822334, Compound 23

SMILES COc1ccc2ncnc(Nc3ccc(Oc4cc5ncnn5cc4F)c(C)c3)c2c1OC1CCN(C)CC1(F)F

InChI Key InChIKey=FXGTVDHLZGHHIJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 471611   

TargetEpidermal growth factor receptor(Human)
TBA

US Patent
LigandPNGBDBM471611(US10822334, Compound 23)
Affinity DataIC50: >1.00E+4nMAssay Description:EGFR: The compounds' inhibition of target modulation were determined as follows: NCI-H838 cells were sorted in 96 well plates (20000 cells/well) ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
TBA

US Patent
LigandPNGBDBM471611(US10822334, Compound 23)
Affinity DataIC50:  6.17nMAssay Description:HER2: The compounds' inhibition of target modulation were determined as follows: BT474 cells were sorted in 96 well plates (20000 cells/well) wit...More data for this Ligand-Target Pair
In DepthDetails US Patent