BDBM472001 CIS-1-Butyl-8-dimethylamino-3-[(4-methoxyphenyl)-methyl]-8-phenyl-1,3- diazaspiro[4.5]decan-2-one::US10829480, Example SC_2015

SMILES CCCCN1C(=O)N(Cc2ccc(OC)cc2)C[C@]11CC[C@@](CC1)(N(C)C)c1ccccc1

InChI Key InChIKey=AXVAABMMWSPIFS-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 472001   

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM472001(CIS-1-Butyl-8-dimethylamino-3-[(4-methoxyphenyl)-m...)
Affinity DataKi:  6.40nMAssay Description:Mu-Opioid Peptide (hMOP): The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent

TargetNociceptin receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM472001(CIS-1-Butyl-8-dimethylamino-3-[(4-methoxyphenyl)-m...)
Affinity DataKi:  162nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent