BDBM47425 2-chloranyl-N-[(2,3-dimethylcyclohexyl)carbamoyl]ethanamide::2-chloro-N-[(2,3-dimethylcyclohexyl)carbamoyl]acetamide::2-chloro-N-[[(2,3-dimethylcyclohexyl)amino]-oxomethyl]acetamide::MLS000391455::SMR000260491::cid_5010280

SMILES CC[C@H]1OCC[C@@]1(N)COc4cc(c2cnc3cccc(OC)n23)cc(SC)c4C#N

InChI Key InChIKey=HMBFDDSLYMRBIX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 47425   

TargetSerine/threonine-protein kinase SIK1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 47425BDBM47425(US20240124450, Example 11B)
Affinity DataIC50: 0.200nMAssay Description:Salt Induced Kinase (SIK) activity is determined by measuring the effect of a test agent on the activity of the appropriate SIK enzyme to phosphoryla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 47425BDBM47425(US20240124450, Example 11B)
Affinity DataIC50: 0.5nMAssay Description:Salt Induced Kinase (SIK) activity is determined by measuring the effect of a test agent on the activity of the appropriate SIK enzyme to phosphoryla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK3(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 47425BDBM47425(US20240124450, Example 11B)
Affinity DataIC50: 1.60nMAssay Description:Salt Induced Kinase (SIK) activity is determined by measuring the effect of a test agent on the activity of the appropriate SIK enzyme to phosphoryla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent