BDBM474337 7-(azetidin-l-yl)-2-(2,6-difluorobenzyl)-8-(3-met hylimidazo[1,2-a]pyridin-6-yl)-[1,2,4]triazolo [1,5-c]pyrimidin-5-amine::US10858365, Compound 124
SMILES Cc1cnc2ccc(cn12)-c1c(nc(N)n2nc(Cc3c(F)cccc3F)nc12)N1CCC1
InChI Key InChIKey=URTMYPIBRWXCIE-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 474337
Affinity DataIC50: 0.100nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
Affinity DataIC50: 23.3nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair