BDBM474338 (R)-7-(4-fluorophenyl)-8-(3-methylimidazo[l,2- a]pyrdin-6-yl)-2-((1-methylpyrrolidin-2-yl )meth yl)-[l,2,4]triazolo[l,5-c]pyrimidin-5-amine::US10858365, Compound 125
SMILES CN1CCC[C@@H]1Cc1nc2c(-c3ccc4ncc(C)n4c3)c(nc(N)n2n1)-c1ccc(F)cc1
InChI Key InChIKey=BFJGLGUWQKURET-LJQANCHMSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 474338
Affinity DataIC50: 34.1nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair