BDBM474339 2-(2-methoxyethyl)-8-(3-methylimidazo[l,2-a] pyridin-6-yl)-7-(oxazol-2-yl)-[1,2,4]triazolo[1,5- c]pyrimidin-5-amine::US10858365, Compound 126

SMILES COCCc1nc2c(-c3ccc4ncc(C)n4c3)c(nc(N)n2n1)-c1ncco1

InChI Key InChIKey=KJEPUKDZBLUKNF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474339   

TargetAdenosine receptor A1(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM474339(2-(2-methoxyethyl)-8-(3-methylimidazo[l,2-a] pyrid...)
Affinity DataIC50:  83.6nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM474339(2-(2-methoxyethyl)-8-(3-methylimidazo[l,2-a] pyrid...)
Affinity DataIC50:  1.10nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent