BDBM47439 (2,6-dimethyl-4-quinolyl)-(4-nitrophenyl)amine::2,6-dimethyl-N-(4-nitrophenyl)-4-quinolinamine::2,6-dimethyl-N-(4-nitrophenyl)quinolin-4-amine::MLS000710716::SMR000280483::cid_2892697

SMILES COc5cc(c1cnc2cccc(OC)n12)cc(OC[C@@]3(N)CCCC34CCCC4)c5C#N

InChI Key InChIKey=UJKFQZSNQANFHU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 47439   

TargetSerine/threonine-protein kinase SIK1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 47439BDBM47439(US20240124450, Example 20B)
Affinity DataIC50: 0.5nMAssay Description:Salt Induced Kinase (SIK) activity is determined by measuring the effect of a test agent on the activity of the appropriate SIK enzyme to phosphoryla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 47439BDBM47439(US20240124450, Example 20B)
Affinity DataIC50: 0.800nMAssay Description:Salt Induced Kinase (SIK) activity is determined by measuring the effect of a test agent on the activity of the appropriate SIK enzyme to phosphoryla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK3(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 47439BDBM47439(US20240124450, Example 20B)
Affinity DataIC50: 3.90nMAssay Description:Salt Induced Kinase (SIK) activity is determined by measuring the effect of a test agent on the activity of the appropriate SIK enzyme to phosphoryla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
US Patent