BDBM47603 (5E)-2-(4-hydroxyanilino)-5-(4-hydroxy-3,5-dimethoxy-benzylidene)-2-thiazolin-4-one::(5E)-2-(4-hydroxyanilino)-5-[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]-1,3-thiazol-4-one::(5E)-2-(4-hydroxyanilino)-5-[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]-4-thiazolone::(5E)-5-[(3,5-dimethoxy-4-oxidanyl-phenyl)methylidene]-2-[(4-hydroxyphenyl)amino]-1,3-thiazol-4-one::(5Z)-2-(4-hydroxyanilino)-5-(4-hydroxy-3,5-dimethoxy-benzylidene)-2-thiazolin-4-one::MLS000715043::SMR000275022::cid_5768667

SMILES COc1cc(C=C2SC(Nc3ccc(O)cc3)=NC2=O)cc(OC)c1O

InChI Key InChIKey=PCLFSFQEDFZNSB-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 47603   

LigandPNGBDBM47603(MLS000715043 | (5E)-2-(4-hydroxyanilino)-5-[(4-hyd...)
Affinity DataEC50:  974nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2011
Entry Details
PCBioAssay
TargetUbiquitin-conjugating enzyme E2 N(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM47603(MLS000715043 | (5E)-2-(4-hydroxyanilino)-5-[(4-hyd...)
Affinity DataIC50: 2.00E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetProtein LANA1(HHV-8)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM47603(MLS000715043 | (5E)-2-(4-hydroxyanilino)-5-[(4-hyd...)
Affinity DataEC50: >7.50E+4nMAssay Description:Primary Collaborators: Kenneth Kaye,Brigham & Womens,Boston MA,kkaye@rics.bwh.harvard.edu,617-525-4256 Chantal Beauchemin,Brigham & Womens,Boston MA,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2011
Entry Details
PCBioAssay
TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM47603(MLS000715043 | (5E)-2-(4-hydroxyanilino)-5-[(4-hyd...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay