BDBM476394 2-chlorophenyl (3S)-3-{[4- (aminomethyl)-3- chlorobenzyl]carbamoyl}-4-(3- cyclohexyl-D-alanyl)piperazine-1- carboxylate::US10875851, Example 50

SMILES NCc1ccc(CNC(=O)[C@@H]2CN(CCN2C(=O)[C@H](N)CC2CCCCC2)C(=O)Oc2ccccc2Cl)cc1Cl

InChI Key InChIKey=DQAVWCRHHUDZSE-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476394   

TargetCoagulation factor XII(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 476394BDBM476394(2-chlorophenyl (3S)-3-{[4- (aminomethyl)-3- chloro...)
Affinity DataIC50: 29.2nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIIa can be determined using a relevant purified serin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
US Patent