BDBM476528 5-(2,2,2-trifluoroethoxy)-N-((8 endo)-3-(2-(trifluoromethyl)pyridin-4-yl)-3-azabicyclo[3.2.1]octan-8-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine::US10875854, Example 1

SMILES FC(F)(F)COc1cccc2nc(N[C@H]3[C@H]4CC[C@@H]3CN(C4)c3ccnc(c3)C(F)(F)F)nn12

InChI Key

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476528   

LigandPNGBDBM476528(5-(2,2,2-trifluoroethoxy)-N-((8 endo)-3-(2-(triflu...)
Affinity DataEC50:  43.6nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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Date in BDB:
7/25/2021
Entry Details
US Patent